› 2aiu

X-ray diffraction
1.6Å resolution

Crystal Structure of Mouse Testicular Cytochrome C at 1.6 Angstrom

Released:
DOI: 10.2210/pdb2aiu/pdb
PDB entry 2aiu coloured by chain, front view.
PDB entry 2aiu coloured by chain, side view.
PDB entry 2aiu coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis.
Liu Z, Lin H, Ye S, Liu QY, Meng Z, Zhang CM, Xia Y, Margoliash E, Rao Z, Liu XJ
Proc Natl Acad Sci U S A 103 8965-70 (2006)
PMID: 16757556

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132219 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c, testis-specific Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00015 (Residues: 1-105; Coverage: 100%)
Gene name: Cyct
Sequence domains: Cytochrome c
Structure domains: Cytochrome c-like domain

Ligands and Environments

2 bound ligands:
Ligand PO4 2 x PO4
Ligand HEM 1 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: I41
Unit cell:
a: 73.98Å b: 73.98Å c: 33.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.178 0.207
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Antioxidant systems and oxidative stress in the testes.
Aitken et al. (2008)
16 more

3 mentions without citation

Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis.
Liu et al. (2006)
2 more