2ain Summary


Solution structure of the AF-6 PDZ domain complexed with the C-terminal peptide from the Bcr protein

The structure was published by Chen, Q., Niu, X., Xu, Y., Wu, J., and Shi, Y., in 2007 in a paper entitled "Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Afadin and 6-mer peptide from Breakpoint cluster region protein.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Afadin P55196 (1003-1094) (AFAD_HUMAN)search Homo sapienssearch < 90% 93 100%
B 6-mer peptide from Breakpoint cluster region protein P11274 (1266-1271) (BCR_HUMAN)search Homo sapienssearch < 90% 6 100%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P55196 (1003 - 1094) Afadin Homo sapiens
P11274 (1266 - 1271) 6-mer peptide from Breakpoint cluster region protein

Chain Structural classification (CATH) Sequence family (Pfam)
A Pdz3 Domainsearch PDZ domain (Also known as DHR or GLGF)search
Chain InterPro annotation
A PDZ domainsearch