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EBI PDBe PDBeView

PDBe Entry: 2ahr view

Crystal Structures of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus pyogenes
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.15 Å, R-factor: 17.51%, Free R-factor: 20.965%, Spacegroup: C 1 2 1
Released 13/09/2005, deposition: 28/07/2005, last revision: 24/02/2009
Authors Nocek, B.search; Lezondra, L.search; Holzle, D.search; Joachimiak, A.search; Midwest Center for Structural Genomics (MCSG)search
Primary citation Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes
J.MOL.BIOL.search vol:354, pag:91-106 (2005) [PubMed ID 16233902 ]search
Keywords 1-Pyrroline-5-Carboxylate Reductasesearch, Pyrroline-5-Carboxylate Reductasesearch, Pyrroline Reductasesearch, Proline biosynthesissearch, NAD(P)binding proteinsearch, Rossmann Foldsearch, Doain swappingsearch, human pathogensearch, Streptococcus pyogenessearch, Structural Genomicssearch, MCSGsearch, PSIsearch, Protein Structure Initiativesearch, Midwest Center for Structural Genomicssearch, OXIDOREDUCTASEsearch
EC 1.5.1.2 ExPASy BRENDA search (A B C D E)
Organism Streptococcus pyogenes M1 GAS 160490search(A B C D E)
UniProt Putative pyrroline carboxylate reductase (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase) Q9A1S9search (A B C D E)
Solvent A, B, C, D, E
Related entries 1yqg, 2ag8
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D, E putative pyrroline carboxylate reductase Protein Q9A1S9 (Q9A1S9_STRP1)search
 259 100%
Heterogens
Id Name Ligands
A, B, C, D, E SODIUM ION NA search
A, B, C, D, E NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE NAP search
A, B, C, D, E FORMIC ACID FMT search
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