2adj Summary

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Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Calcium

The structure was published by Zhou, T., Hamer, D.H., Hendrickson, W.A., Sattentau, Q.J., and Kwong, P.D., in 2005 in a paper entitled "Interfacial metal and antibody recognition." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Q425 Fab Light chain and Q425 Fab Heavy chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Q425 Fab Light chain Not available
Mus musculussearch Not available 214 98%
B Q425 Fab Heavy chain Not available
Mus musculussearch Not available 222 96%


Chain Structural classification (SCOP) Structural classification (CATH)
A Immunoglobulinssearch
B C1 set domains (antibody constant domain-like)search Immunoglobulinssearch
Chain InterPro annotation
A Immunoglobulin/major histocompatibility complex, conserved sitesearch search Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch
B search Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch