Crystal Structure of an active site mutant, C473S, of Cdc25B Phosphatase Catalytic Domain
The structure was published by Sohn, J., Parks, J.M., Buhrman, G., et al., Edelsbrunner, H., Yang, W., and Rudolph, J., in 2005 in a paper entitled "Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2-CycA Protein Substrate." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.52 Å and deposited in 2005.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of M-phase inducer phosphatase 2. This molecule has the UniProt identifier P30305 (MPIP2_HUMAN). The sample contained 175 residues which is < 90% of the natural sequence. Out of 175 residues 171 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: