› 2z0o

X-ray diffraction
2.58Å resolution

Crystal structure of APPL1-BAR-PH domain

Released:
DOI: 10.2210/pdb2z0o/pdb
PDB entry 2z0o coloured by chain, front view.
PDB entry 2z0o coloured by chain, side view.
PDB entry 2z0o coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Murayama K, Kato-Murayama M, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCC-interacting protein 13-alpha Chain: A
Molecule details ›
Chain: A
Length: 387 amino acids
Theoretical weight: 45 KDa
Source organism: Homo sapiens
Expression system: cell-free protein synthesis
UniProt:
  • Canonical: Q9UKG1 (Residues: 1-385; Coverage: 54%)
Gene names: APPL, APPL1, DIP13A, KIAA1428
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 15 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21212
Unit cell:
a: 103.449Å b: 111.003Å c: 36.853Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.235 0.299
Expression system: cell-free protein synthesis

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