› 2xu6

X-ray diffraction
2.7Å resolution

MDV1 coiled coil domain

Released:
DOI: 10.2210/pdb2xu6/pdb
PDB entry 2xu6 coloured by chain, front view.
PDB entry 2xu6 coloured by chain, side view.
PDB entry 2xu6 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes.
Koirala S, Bui HT, Schubert HL, Eckert DM, Hill CP, Kay MS, Shaw JM
J Cell Biol 191 1127-39 (2010)
PMID: 21149566

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155576 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial division protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 72 amino acids
Theoretical weight: 8.54 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P47025 (Residues: 231-300; Coverage: 10%)
Gene names: FIS2, GAG3, J0802, MDV1, NET2, YJL112W
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P41212
Unit cell:
a: 41.38Å b: 41.38Å c: 227.378Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.273 0.27 0.314
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

New insights into the function and regulation of mitochondrial fission.
Otera et al. (2013)
7 more

5 mentions without citation

Templated chemistry for bioorganic synthesis and chemical biology.
Seitz O. (2019)
4 more