2xq9

X-ray diffraction
3.2Å resolution

Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-181806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proton-gated ion channel Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 317 amino acids
Theoretical weight: 36.26 KDa
Source organism: Gloeobacter violaceus PCC 7421
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7NDN8 (Residues: 43-359; Coverage: 100%)
Gene names: glr4197, glvI
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 183.314Å b: 128.31Å c: 164.374Å
α: 90° β: 104.04° γ: 90°
R-values:
R R work R free
0.252 0.252 0.257
Expression system: Escherichia coli BL21(DE3)