› 2xb0

X-ray diffraction
2Å resolution

DNA-binding domain from Saccharomyces cerevisiae chromatin- remodelling protein Chd1

Released:
DOI: 10.2210/pdb2xb0/pdb
PDB entry 2xb0 coloured by chain, front view.
PDB entry 2xb0 coloured by chain, side view.
PDB entry 2xb0 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains.
Ryan DP, Sundaramoorthy R, Martin D, Singh V, Owen-Hughes T
EMBO J 30 2596-609 (2011)
PMID: 21623345

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152419 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromo domain-containing protein 1 Chain: X
Molecule details ›
Chain: X
Length: 270 amino acids
Theoretical weight: 30.31 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P32657 (Residues: 1009-1274; Coverage: 18%)
Gene names: CHD1, SYGP-ORF4, YER164W
Sequence domains: Chromodomain helicase DNA-binding domain 1
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand GOL 2 x GOL
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 37.45Å b: 91.12Å c: 98.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.205 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

23 review citations

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes.
Narlikar et al. (2013)
22 more

4 mentions without citation

Snf2-family proteins: chromatin remodellers for any occasion.
Ryan et al. (2011)
3 more