2wt8

X-ray diffraction
1.6Å resolution

Structure of the N-terminal BRCT domain of human microcephalin (Mcph1)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185512 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microcephalin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 97 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NEM0 (Residues: 1-95; Coverage: 11%)
Gene name: MCPH1
Sequence domains: twin BRCT domain
Structure domains: BRCT domain

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 80.955Å b: 34.215Å c: 84.23Å
α: 90° β: 113.53° γ: 90°
R-values:
R R work R free
0.192 0.19 0.222
Expression system: Escherichia coli