› 2rup

Solution NMR

Solution structure of rat P2X4 receptor head domain

Released:
DOI: 10.2210/pdb2rup/pdb
PDB entry 2rup coloured by chain, ensemble of 20 models, front view.
PDB entry 2rup coloured by chain, ensemble of 20 models, side view.
PDB entry 2rup coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.
Igawa T, Abe Y, Tsuda M, Inoue K, Ueda T
FEBS Lett 589 680-6 (2015)
PMID: 25662851

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156363 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
P2X purinoceptor 4 Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.07 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P51577 (Residues: 111-167; Coverage: 15%)
Gene name: P2rx4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 94%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

6 review citations

P2X4: A fast and sensitive purinergic receptor.
Suurväli et al. (2017)
5 more

2 mentions without citation

The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors.
Pasqualetto et al. (2018)
1 more