› 2rq9

Solution NMR

Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new

Released:
DOI: 10.2210/pdb2rq9/pdb
PDB entry 2rq9 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rq9 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rq9 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Enomoto M, Xiang L, Ishii T, Tochio N, Hosoda K, Inoue Y, Nameki N, Wakamatsu K

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 1 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.43 KDa
Source organism: Homo sapiens
Expression system: E. coli cell free protein synthesis
UniProt:
  • Canonical: P05230 (Residues: 22-155; Coverage: 87%)
Gene names: FGF1, FGFA
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: E. coli cell free protein synthesis

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