Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132685 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Epidermal growth factor receptor
Molecule details ›
Chains: A, B
Length: 324 amino acids
Theoretical weight: 36.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Length: 324 amino acids
Theoretical weight: 36.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00533 (Residues: 702-1022; Coverage: 27%)
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
ERBB receptor feedback inhibitor 1
Molecule details ›
Chains: C, D
Length: 25 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: EGFR receptor inhibitor Mig-6
Length: 25 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q9UJM3 (Residues: 340-364; Coverage: 5%)
Sequence domains: EGFR receptor inhibitor Mig-6
