› 2rak

X-ray diffraction
3Å resolution

PI(3)P bound PX-BAR membrane remodeling unit of Sorting Nexin 9

Released:
DOI: 10.2210/pdb2rak/pdb
PDB entry 2rak coloured by chain, front view.
PDB entry 2rak coloured by chain, side view.
PDB entry 2rak coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The PX-BAR membrane-remodeling unit of sorting nexin 9.
Pylypenko O, Lundmark R, Rasmuson E, Carlsson SR, Rak A
EMBO J 26 4788-800 (2007)
PMID: 17948057

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195298 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-9 Chain: A
Molecule details ›
Chain: A
Length: 392 amino acids
Theoretical weight: 45.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y5X1 (Residues: 204-595; Coverage: 66%)
Gene names: SH3PX1, SH3PXD3A, SNX9
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PIB 1 x PIB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2221
Unit cell:
a: 64.059Å b: 144.177Å c: 118.245Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.293
Expression system: Escherichia coli

Quick links

Citations

34 review citations

Retromer.
Bonifacino et al. (2008)
33 more

9 mentions without citation

Translation of the phosphoinositide code by PI effectors.
Kutateladze TG. (2010)
8 more