Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-163204 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Mitotic spindle assembly checkpoint protein MAD2A
Molecule details ›
Chains: A, C
Length: 206 amino acids
Theoretical weight: 23.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: HORMA domain
Structure domains: HORMA domain
Length: 206 amino acids
Theoretical weight: 23.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q13257 (Residues: 1-205; Coverage: 100%)
Sequence domains: HORMA domain
Structure domains: HORMA domain
MAD2L1-binding protein
Molecule details ›
Chains: B, D
Length: 240 amino acids
Theoretical weight: 27.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Mad1 and Cdc20-bound-Mad2 binding
Structure domains: Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A
Length: 240 amino acids
Theoretical weight: 27.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q15013 (Residues: 36-274; Coverage: 87%)
Sequence domains: Mad1 and Cdc20-bound-Mad2 binding
Structure domains: Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A
