› 2qw4

X-ray diffraction
2.8Å resolution

Human NR4A1 ligand-binding domain

Released:
DOI: 10.2210/pdb2qw4/pdb
PDB entry 2qw4 coloured by chain, front view.
PDB entry 2qw4 coloured by chain, side view.
PDB entry 2qw4 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Min JR, Schuetz A, Loppnau P, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149784 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor subfamily 4immunitygroup A member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 273 amino acids
Theoretical weight: 30.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22736 (Residues: 347-598; Coverage: 42%)
Gene names: GFRP1, HMR, NAK1, NR4A1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 89.53Å b: 96.364Å c: 144.849Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.23 0.292
Expression system: Escherichia coli

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