Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
cAMP-dependent protein kinase (preferred)
PDBe Complex ID:
PDB-CPX-138539 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP-dependent protein kinase catalytic subunit alpha
Molecule details ›
Chain: E
Length: 350 amino acids
Theoretical weight: 40.66 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 350 amino acids
Theoretical weight: 40.66 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P05132 (Residues: 2-351; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
cAMP-dependent protein kinase type II-alpha regulatory subunit
Molecule details ›
Chain: B
Length: 310 amino acids
Theoretical weight: 35.3 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls
Length: 310 amino acids
Theoretical weight: 35.3 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P12367 (Residues: 92-401; Coverage: 77%)
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls
