› 2qop

X-ray diffraction
2.55Å resolution

Crystal structure of the transcriptional regulator AcrR from Escherichia coli

Released:
DOI: 10.2210/pdb2qop/pdb
PDB entry 2qop coloured by chain, front view.
PDB entry 2qop coloured by chain, side view.
PDB entry 2qop coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Crystal structure of the transcriptional regulator AcrR from Escherichia coli.
Li M, Gu R, Su CC, Routh MD, Harris KC, Jewell ES, McDermott G, Yu EW
J Mol Biol 374 591-603 (2007)
PMID: 17950313

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142297 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator AcrR Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 24.8 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P0ACS9 (Residues: 1-215; Coverage: 100%)
Gene names: JW0453, acrR, b0464, ybaH
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P2221
Unit cell:
a: 48.218Å b: 54.574Å c: 73.726Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.273
Expression system: Escherichia coli K-12

Quick links

Citations

10 review citations

Efflux-mediated drug resistance in bacteria: an update.
Li et al. (2009)
9 more

3 mentions without citation

The TetR family of regulators.
Cuthbertson et al. (2013)
2 more