› 2qcv

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF a putative 5-dehydro-2-deoxygluconokinase (IOLC) FROM BACILLUS HALODURANS C-125 AT 1.90 A RESOLUTION

Released:
DOI: 10.2210/pdb2qcv/pdb
PDB entry 2qcv coloured by chain, front view.
PDB entry 2qcv coloured by chain, side view.
PDB entry 2qcv coloured by chain, top view.
Source organism: Alkalihalobacillus halodurans C-125
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191811 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-dehydro-2-deoxygluconokinase Chain: A
Molecule details ›
Chain: A
Length: 332 amino acids
Theoretical weight: 37.02 KDa
Source organism: Alkalihalobacillus halodurans C-125
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KAG8 (Residues: 1-331; Coverage: 100%)
Gene names: BH2319, iolC
Sequence domains: pfkB family carbohydrate kinase
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PGE 2 x PGE
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P6422
Unit cell:
a: 194.001Å b: 194.001Å c: 48.083Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.175 0.196
Expression system: Escherichia coli

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