Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA-directed DNA polymerase, family B
- DNA-directed DNA polymerase, family B, conserved site
- DNA/RNA polymerase superfamily
- DNA polymerase, palm domain superfamily
- DNA-directed DNA polymerase, family B, mitochondria/virus
- Ribonuclease H-like superfamily
- DNA-directed DNA polymerase, family B, phi29-like virus
- Ribonuclease H superfamily
Structure domains:
Structure analysis Details
Assemblies composition:
Assembly name:
DNA polymerase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-115793 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
DNA polymerase
Molecule details ›
Chains: A, B, C, D
Length: 575 amino acids
Theoretical weight: 66.72 KDa
Source organism: Bacillus virus phi29
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA polymerase type B, organellar and viral
Structure domains:
Length: 575 amino acids
Theoretical weight: 66.72 KDa
Source organism: Bacillus virus phi29
Expression system: Escherichia coli
UniProt:
- Canonical:
P03680 (Residues: 1-575; Coverage: 100%)
Sequence domains: DNA polymerase type B, organellar and viral
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
C2
Expression systems:
- Escherichia coli
- Not provided
