› 2p01

Solution NMR

The structure of receptor-associated protein(RAP)

Released:
DOI: 10.2210/pdb2p01/pdb
PDB entry 2p01 coloured by chain, ensemble of 20 models, front view.
PDB entry 2p01 coloured by chain, ensemble of 20 models, side view.
PDB entry 2p01 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of receptor-associated protein (RAP).
Lee D, Walsh JD, Migliorini M, Yu P, Cai T, Schwieters CD, Krueger S, Strickland DK, Wang YX
Protein Sci 16 1628-40 (2007)
PMID: 17656581

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151758 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-2-macroglobulin receptor-associated protein Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 37.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P30533 (Residues: 35-357; Coverage: 100%)
Gene names: A2MRAP, LRPAP1
Sequence domains:
Structure domains: RAP domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SANS measurement

Quick links

Citations

2 review citations

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies.
Lillis et al. (2008)
1 more

4 mentions without citation

Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP.
Jensen et al. (2009)
3 more