› 2oz9

X-ray diffraction
1.65Å resolution

E. coli TRP holorepressor, orthorhombic crystal form

Released:
DOI: 10.2210/pdb2oz9/pdb
PDB entry 2oz9 coloured by chain, front view.
PDB entry 2oz9 coloured by chain, side view.
PDB entry 2oz9 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Flexibility of the DNA-binding domains of trp repressor.
Lawson CL, Zhang RG, Schevitz RW, Otwinowski Z, Joachimiak A, Sigler PB
Proteins 3 18-31 (1988)
PMID: 3375234

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trp operon repressor Chain: R
Molecule details ›
Chain: R
Length: 107 amino acids
Theoretical weight: 12.24 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A881 (Residues: 2-108; Coverage: 99%)
Gene names: JW4356, b4393, rtrY, trpR
Sequence domains: Trp repressor protein
Structure domains: TrpR-like

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand SO4 1 x SO4
Ligand TRP 1 x TRP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-6
Spacegroup: P21212
Unit cell:
a: 53.3Å b: 53.6Å c: 33.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 not available not available
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Folding funnels and binding mechanisms.
Ma et al. (1999)
8 more

7 mentions without citation

A biosensor for the direct visualization of auxin.
Herud-Sikimić et al. (2021)
6 more