› 2o9q

X-ray diffraction
1.7Å resolution

The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K

Released:
DOI: 10.2210/pdb2o9q/pdb
PDB entry 2o9q coloured by chain, front view.
PDB entry 2o9q coloured by chain, side view.
PDB entry 2o9q coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Li J, Zhang C, Xu X, Wang J, Gong W, Lai R

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133351 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine protease 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
ORB2K Chain: C
Molecule details ›
Chain: C
Length: 17 amino acids
Theoretical weight: 1.89 KDa
Source organism: Bos taurus
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 46.016Å b: 63.451Å c: 69.684Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.155 0.195
Expression system: Not provided

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