Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Tumor protein p73 and Tumor protein 63 (preferred)
PDBe Complex ID:
PDB-CPX-127443 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor protein 63
Molecule details ›
Chains: A, C
Length: 60 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: P53 tetramerisation motif
Length: 60 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q9H3D4 (Residues: 397-455; Coverage: 9%)
Sequence domains: P53 tetramerisation motif
Tumor protein p73
Molecule details ›
Chains: B, D
Length: 50 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: P53 tetramerisation motif
Length: 50 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: O15350 (Residues: 351-398; Coverage: 8%)
Sequence domains: P53 tetramerisation motif
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
86%
Refinement method:
molecular dynamics
Expression system: Escherichia coli BL21
