› 2lk1

Solution NMR

Solution structure and binding studies of the RanBP2-type zinc finger of RBM5

Released:
DOI: 10.2210/pdb2lk1/pdb
PDB entry 2lk1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lk1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lk1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Targeting zinc finger domains with small molecules: solution structure and binding studies of the RanBP2-type zinc finger of RBM5.
Farina B, Fattorusso R, Pellecchia M
Chembiochem 12 2837-45 (2011)
PMID: 22162216

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein 5 Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.73 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P52756 (Residues: 181-210; Coverage: 4%)
Gene names: H37, LUCA15, RBM5
Sequence domains: Zn-finger in Ran binding protein and others

Ligands and Environments

2 bound ligands:
Ligand AQN 1 x AQN
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: simulated annealing, Energy minimization
Expression system: Not provided

Quick links

Citations

1 review citation

RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer.
Soubise et al. (2022)
7 other articles