› 2l9w

Solution NMR

Solution Structure of the C-terminal domain of Prp24

Released:
DOI: 10.2210/pdb2l9w/pdb
PDB entry 2l9w coloured by chain, ensemble of 20 models, front view.
PDB entry 2l9w coloured by chain, ensemble of 20 models, side view.
PDB entry 2l9w coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop.
Martin-Tumasz S, Richie AC, Clos LJ, Brow DA, Butcher SE
Nucleic Acids Res 39 7837-47 (2011)
PMID: 21653550

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U4/U6 snRNA-associated-splicing factor PRP24 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.85 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P49960 (Residues: 292-400; Coverage: 25%)
Gene names: PRP24, YM8156.10C, YMR268C
Sequence domains: Occluded RNA-recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

RRM-RNA recognition: NMR or crystallography…and new findings.
Daubner et al. (2013)
5 more

3 mentions without citation

A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop.
Martin-Tumasz et al. (2011)
2 more