› 2ktd

Solution NMR

Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex

Released:
DOI: 10.2210/pdb2ktd/pdb
PDB entry 2ktd coloured by chain, ensemble of 15 models, front view.
PDB entry 2ktd coloured by chain, ensemble of 15 models, side view.
PDB entry 2ktd coloured by chain, ensemble of 15 models, top view.
Source organism: Mus musculus
Entry authors: Shimamoto S, Maruo H, Yoshida T, Kato N, Ohkubo T

Function and Biology Details

Reaction catalysed: 
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prostaglandin-H2 D-isomerase Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O09114 (Residues: 25-189; Coverage: 100%)
Gene name: Ptgds
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand PUC 1 x PUC
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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