› 2kmc

Solution NMR

Solution Structure of the N-terminal domain of kindlin-1

Released:
DOI: 10.2210/pdb2kmc/pdb
PDB entry 2kmc coloured by chain, ensemble of 20 models, front view.
PDB entry 2kmc coloured by chain, ensemble of 20 models, side view.
PDB entry 2kmc coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.
Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR
J Mol Biol 394 944-56 (2009)
PMID: 19804783

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157775 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fermitin family homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.67 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P59113 (Residues: 1-96; Coverage: 14%)
Gene names: Fermt1, Kind1, Urp1
Sequence domains: Kindlin-2 N-terminal domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Cell adhesion: integrating cytoskeletal dynamics and cellular tension.
Parsons et al. (2010)
16 more

3 mentions without citation

The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.
Goult et al. (2009)
2 more