› 2kjc

Solution NMR

Solution structure of CzrA in the Zn(II) state

Released:
DOI: 10.2210/pdb2kjc/pdb
PDB entry 2kjc coloured by chain, ensemble of 21 models, front view.
PDB entry 2kjc coloured by chain, ensemble of 21 models, side view.
PDB entry 2kjc coloured by chain, ensemble of 21 models, top view.
Source organism: Staphylococcus aureus
Primary publication:
Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state.
Arunkumar AI, Campanello GC, Giedroc DP
Proc Natl Acad Sci U S A 106 18177-82 (2009)
PMID: 19822742

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH arsR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 106 amino acids
Theoretical weight: 11.99 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: O85142 (Residues: 1-106; Coverage: 100%)
Gene names: A6760_11845, BN1321_350009, CV021_10345, CzrA, EP54_06885, EQ90_13065, FAF17_13815, G6W63_05680, G6Y24_05035, GO793_16165, GO814_05535, GO941_16585, GO942_06145, GQX37_08730, GZ156_05085, GZ163_08250, H2639_10805, HMPREF3211_00009, M1K003_2263, NCTC10702_03381, NCTC13131_01480, NCTC5664_01801, NCTC6133_02909, NCTC7878_02904, NCTC7972_02574, QU38_06130, SAMEA2078260_01939, SAMEA2078588_01910, SAMEA2080344_01776, SAMEA2081063_01791, SAMEA4008575_00680, SAMEA70146418_02191, SAMEA70153168_02326, SAMEA70245418_02324, czrA, czrA_1, czrA_2, rzcA
Sequence domains: Bacterial regulatory protein, arsR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Metalloregulatory proteins: metal selectivity and allosteric switching.
Reyes-Caballero et al. (2011)
10 more

4 mentions without citation

Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state.
Arunkumar et al. (2009)
3 more