› 2k3x

Solution NMR

Solution structure of EAF3 chromo barrel domain

Released:
DOI: 10.2210/pdb2k3x/pdb
PDB entry 2k3x coloured by chain, ensemble of 20 models, front view.
PDB entry 2k3x coloured by chain, ensemble of 20 models, side view.
PDB entry 2k3x coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis for the recognition of methylated histone H3K36 by the Eaf3 subunit of histone deacetylase complex Rpd3S.
Xu C, Cui G, Botuyan MV, Mer G
Structure 16 1740-50 (2008)
PMID: 18818090

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171359 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromatin modification-related protein EAF3 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 14.1 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12432 (Residues: 1-113; Coverage: 28%)
Gene names: EAF3, YP9367.03C, YPR023C
Sequence domains: RNA binding activity-knot of a chromodomain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Perceiving the epigenetic landscape through histone readers.
Musselman et al. (2012)
18 more

3 mentions without citation

Touch, act and go: landing and operating on nucleosomes.
Speranzini et al. (2016)
2 more