› 2jzs

Solution NMR

Solution structure of the reduced form of the N-terminal domain of PilB from N. meningitidis.

Released:
DOI: 10.2210/pdb2jzs/pdb
PDB entry 2jzs coloured by chain, ensemble of 20 models, front view.
PDB entry 2jzs coloured by chain, ensemble of 20 models, side view.
PDB entry 2jzs coloured by chain, ensemble of 20 models, top view.
Source organism: Neisseria meningitidis serogroup A
Primary publication:
Solution structure and dynamics of the reduced and oxidized forms of the N-terminal domain of PilB from Neisseria meningitidis.
Quinternet M, Tsan P, Neiers F, Beaufils C, Boschi-Muller S, Averlant-Petit MC, Branlant G, Cung MT
Biochemistry 47 8577-89 (2008)
PMID: 18651754

Function and Biology Details

Reactions catalysed: 
L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide + thioredoxin
Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191668 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide methionine sulfoxide reductase MsrA/MsrB Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 15.85 KDa
Source organism: Neisseria meningitidis serogroup A
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JWM8 (Residues: 34-176; Coverage: 27%)
Gene names: NMA0290, msrAB, pilB
Sequence domains: Redoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

4 citation in other articles

Molecular architecture of Streptococcus pneumoniae surface thioredoxin-fold lipoproteins crucial for extracellular oxidative stress resistance and maintenance of virulence.
Saleh et al. (2013)
3 more