› 2jwt

Solution NMR

Solution structure of Engrailed homeodomain WT

Released:
DOI: 10.2210/pdb2jwt/pdb
PDB entry 2jwt coloured by chain, ensemble of 25 models, front view.
PDB entry 2jwt coloured by chain, ensemble of 25 models, side view.
PDB entry 2jwt coloured by chain, ensemble of 25 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Comparison of multiple crystal structures with NMR data for engrailed homeodomain.
Religa TL
J Biomol NMR 40 189-202 (2008)
PMID: 18274703

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136264 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Segmentation polarity homeobox protein engrailed Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.47 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P02836 (Residues: 453-512; Coverage: 11%)
Gene names: CG9015, en
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 citation in other articles

Refolding the engrailed homeodomain: structural basis for the accumulation of a folding intermediate.
McCully et al. (2010)
6 more

10 mentions without citation

Fast protein folding kinetics.
Gelman et al. (2014)
9 more