› 2jrf

Solution NMR

Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.

Released:
DOI: 10.2210/pdb2jrf/pdb
PDB entry 2jrf coloured by chain, ensemble of 20 models, front view.
PDB entry 2jrf coloured by chain, ensemble of 20 models, side view.
PDB entry 2jrf coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Aramini JM, Rossi P, Shastry R, Nwosu C, Cunningham K, Xiao R, Liu J, Baran MC, Rajan PK, Acton TB, Rost B, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189771 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tubulin polymerization-promoting protein family member 3 Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BW30 (Residues: 1-176; Coverage: 100%)
Gene names: CGI-38, TPPP3
Sequence domains: p25-alpha
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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