› 2jhb

Solution NMR

CORE BINDING FACTOR BETA

Released:
DOI: 10.2210/pdb2jhb/pdb
PDB entry 2jhb coloured by chain, ensemble of 20 models, front view.
PDB entry 2jhb coloured by chain, ensemble of 20 models, side view.
PDB entry 2jhb coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of core binding factor beta and map of the CBF alpha binding site.
Huang X, Peng JW, Speck NA, Bushweller JH
Nat Struct Biol 6 624-7 (1999)
PMID: 10404216

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170588 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Core-binding factor subunit beta Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.76 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08024 (Residues: 1-141; Coverage: 75%)
Gene names: Cbfb, Pebp2b, Pebpb2
Sequence domains: Core binding factor beta subunit
Structure domains: Core binding factor, beta subunit

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Core-binding factors in haematopoiesis and leukaemia.
Speck et al. (2002)
15 more

4 mentions without citation

Probability-based protein secondary structure identification using combined NMR chemical-shift data.
Wang et al. (2002)
3 more