› 2iyl

X-ray diffraction
2.1Å resolution

Structure of an FtsY:GDP complex

Released:
DOI: 10.2210/pdb2iyl/pdb
PDB entry 2iyl coloured by chain, front view.
PDB entry 2iyl coloured by chain, side view.
PDB entry 2iyl coloured by chain, top view.
Source organism: Thermus aquaticus
Primary publication:
X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.
Gawronski-Salerno J, Coon JS, Focia PJ, Freymann DM
Proteins 66 984-95 (2007)
PMID: 17186523

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal recognition particle receptor FtsY Chain: D
Molecule details ›
Chain: D
Length: 284 amino acids
Theoretical weight: 30.76 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P83749 (Residues: 21-304; Coverage: 93%)
Gene name: ftsY
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand GDP 1 x GDP
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: I4
Unit cell:
a: 105.196Å b: 105.196Å c: 54.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.207 0.291
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Signal recognition particle: an essential protein-targeting machine.
Akopian et al. (2013)
2 more

4 mentions without citation

Protein-protein docking benchmark version 4.0.
Hwang et al. (2010)
3 more