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X-ray diffraction
2.54Å resolution

Function and Biology Details

Reaction catalysed: 
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190946 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dTDP-4-dehydrorhamnose 3,5-epimerase Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 21.08 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HU21 (Residues: 1-181; Coverage: 100%)
Gene names: PA5164, rmlC
Sequence domains: dTDP-4-dehydrorhamnose 3,5-epimerase
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand SRT 1 x SRT
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 57.833Å b: 57.833Å c: 161.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.278
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Review: Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa.
King et al. (2009)
9 more

2 mentions without citation

RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation.
Dong et al. (2007)
1 more