› 2igl

X-ray diffraction
1.8Å resolution

Crystal Structure of E. coli YEDX, a transthyretin related protein

Released:
DOI: 10.2210/pdb2igl/pdb
PDB entry 2igl coloured by chain, front view.
PDB entry 2igl coloured by chain, side view.
PDB entry 2igl coloured by chain, top view.
Source organism: Escherichia coli K-12
Entry authors: Zuo Y, Malhotra A

Function and Biology Details

Reaction catalysed: 
5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160079 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-hydroxyisourate hydrolase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 118 amino acids
Theoretical weight: 13.44 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P76341 (Residues: 24-137; Coverage: 100%)
Gene names: JW1953, b1970, hiuH, yedX
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 58.12Å b: 77.37Å c: 100.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.242
Expression system: Escherichia coli

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