› 2hh3

Solution NMR

Solution structure of the third KH domain of KSRP

Released:
DOI: 10.2210/pdb2hh3/pdb
PDB entry 2hh3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2hh3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2hh3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation.
García-Mayoral MF, Hollingworth D, Masino L, Díaz-Moreno I, Kelly G, Gherzi R, Chou CF, Chen CY, Ramos A
Structure 15 485-98 (2007)
PMID: 17437720

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187817 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Far upstream element-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92945 (Residues: 318-418; Coverage: 14%)
Gene names: FUBP2, KHSRP
Sequence domains: KH domain
Structure domains: K Homology domain, type 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Structure and function of KH domains.
Valverde et al. (2008)
21 more

3 mentions without citation

Protein-RNA specificity by high-throughput principal component analysis of NMR spectra.
Collins et al. (2015)
2 more