› 2glh

Solution NMR

Solution Conformation of Salmon Calcitonin in Sodium Dodecyl Sulfate Micelles

Released:
DOI: 10.2210/pdb2glh/pdb
PDB entry 2glh coloured by chain, ensemble of 100 models, front view.
PDB entry 2glh coloured by chain, ensemble of 100 models, side view.
PDB entry 2glh coloured by chain, ensemble of 100 models, top view.
Source organism: Oncorhynchus keta
Primary publication:
Structural determinants of salmon calcitonin bioactivity: the role of the Leu-based amphipathic alpha-helix.
Andreotti G, Méndez BL, Amodeo P, Morelli MA, Nakamuta H, Motta A
J Biol Chem 281 24193-203 (2006)
PMID: 16766525

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134136 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcitonin-1 Chain: A
Molecule details ›
Chain: A
Length: 33 amino acids
Theoretical weight: 3.44 KDa
Source organism: Oncorhynchus keta
Expression system: Not provided
UniProt:
  • Canonical: P01263 (Residues: 83-114; Coverage: 29%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: restrained simulated annealing/energy minimization followed by unrestrained molecular dynamics
Expression system: Not provided

Quick links

Citations

5 review citations

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
Parthier et al. (2009)
4 more

11 mentions without citation

Protein-polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications.
Grover et al. (2010)
10 more