› 2f68

X-ray diffraction
1.95Å resolution

Crystal structure of collagen adhesin (CNA) from S. aureus

Released:
DOI: 10.2210/pdb2f68/pdb
PDB entry 2f68 coloured by chain, front view.
PDB entry 2f68 coloured by chain, side view.
PDB entry 2f68 coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen.
Zong Y, Xu Y, Liang X, Keene DR, Höök A, Gurusiddappa S, Höök M, Narayana SV
EMBO J 24 4224-36 (2005)
PMID: 16362049

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen adhesin Chain: X
Molecule details ›
Chain: X
Length: 313 amino acids
Theoretical weight: 34.39 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q53654 (Residues: 30-334; Coverage: 26%)
Gene name: cna
Sequence domains: Collagen binding domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 41.982Å b: 106.427Å c: 44.083Å
α: 90° β: 116.44° γ: 90°
R-values:
R R work R free
0.292 0.195 0.253
Expression system: Escherichia coli BL21

Quick links

Citations

38 review citations

Mammalian collagen receptors.
Leitinger et al. (2007)
37 more

11 mentions without citation

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus.
Foster et al. (2014)
10 more