› 2ebo

X-ray diffraction
1.9Å resolution

CORE STRUCTURE OF GP2 FROM EBOLA VIRUS

Released:
DOI: 10.2210/pdb2ebo/pdb
PDB entry 2ebo coloured by chain, front view.
PDB entry 2ebo coloured by chain, side view.
PDB entry 2ebo coloured by chain, top view.
Source organism: Ebola virus - Mayinga, Zaire, 1976
Primary publication:
Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution.
Malashkevich VN, Schneider BJ, McNally ML, Milhollen MA, Pang JX, Kim PS
Proc Natl Acad Sci U S A 96 2662-7 (1999)
PMID: 10077567

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GP2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 74 amino acids
Theoretical weight: 8.54 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q05320 (Residues: 557-630; Coverage: 12%)
Gene name: GP
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P62
Unit cell:
a: 75.66Å b: 75.66Å c: 67.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.205 0.27
Expression system: Escherichia coli BL21

Quick links

Citations

38 review citations

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.
Skehel et al. (2000)
37 more

30 mentions without citation

Virus membrane fusion.
Weissenhorn et al. (2007)
29 more