› 2dc2

Solution NMR

Solution Structure of PDZ Domain

Released:
DOI: 10.2210/pdb2dc2/pdb
PDB entry 2dc2 coloured by chain, ensemble of 20 models, front view.
PDB entry 2dc2 coloured by chain, ensemble of 20 models, side view.
PDB entry 2dc2 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin.
Li X, Zhang J, Cao Z, Wu J, Shi Y
Protein Sci 15 2149-58 (2006)
PMID: 16882988

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190800 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Golgi-associated PDZ and coiled-coil motif-containing protein Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HD26 (Residues: 277-371; Coverage: 21%)
Gene names: CAL, FIG, GOPC
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders.
Shaw et al. (2017)
2 more

5 mentions without citation

A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.
Cushing et al. (2010)
4 more