› 2cwg

X-ray diffraction
2Å resolution

CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE ANALYSIS OF THE COMPLEX OF WHEAT GERM AGGLUTININ WITH A BIVALENT SIALOGLYCOPEPTIDE FROM GLYCOPHORIN A

Released:
DOI: 10.2210/pdb2cwg/pdb
PDB entry 2cwg coloured by chain, front view.
PDB entry 2cwg coloured by chain, side view.
PDB entry 2cwg coloured by chain, top view.
Source organism: Triticum aestivum
Primary publication:
Crystallographic refinement and structure analysis of the complex of wheat germ agglutinin with a bivalent sialoglycopeptide from glycophorin A.
Wright CS, Jaeger J
J. Mol. Biol. 232 620-38 (1993)
PMID: 8345526

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145545 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Agglutinin isolectin 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 171 amino acids
Theoretical weight: 17.12 KDa
Source organism: Triticum aestivum
UniProt:
  • Canonical: P10968 (Residues: 27-197; Coverage: 92%)
Sequence domains: Chitin recognition protein
Structure domains: Endochitinase-like
T5 SIALOGLYCOPEPTIDE OF GLYCOPHORIN A Chains: D, E
Molecule details ›
Chains: D, E
Length: 8 amino acids
Theoretical weight: 895 Da
Source organism: Triticum aestivum
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: NDG, GAL, SIA
Carbohydrate polymer
No bound ligands
1 modified residue:
Ligand PCA 2 x PCA

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 111Å b: 50.4Å c: 63.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.171 not available
Expression system: Not provided

Quick links

Citations

4 review citations

Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses.
Shi et al. (2014)
3 more

6 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
5 more