› 2ciu

X-ray diffraction
1.6Å resolution

Structure of the IMS domain of the mitochondrial import protein Tim21 from S. cerevisiae

Released:
DOI: 10.2210/pdb2ciu/pdb
PDB entry 2ciu coloured by chain, front view.
PDB entry 2ciu coloured by chain, side view.
PDB entry 2ciu coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes.
Albrecht R, Rehling P, Chacinska A, Brix J, Cadamuro SA, Volkmer R, Guiard B, Pfanner N, Zeth K
EMBO Rep 7 1233-8 (2006)
PMID: 17099692

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial import inner membrane translocase subunit TIM21 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P53220 (Residues: 103-225; Coverage: 52%)
Gene names: TIM21, YGR033C
Sequence domains: TIM21
Structure domains: Mitochondrial import inner membrane translocase subunit Tim21

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P212121
Unit cell:
a: 32.31Å b: 58.82Å c: 62.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

24 review citations

Mitochondrial protein import: from proteomics to functional mechanisms.
Schmidt et al. (2010)
23 more

3 mentions without citation

The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes.
Albrecht et al. (2006)
2 more