› 2c88

X-ray diffraction
3.1Å resolution

Crystal Structure Of (SR) Calcium-ATPase E2(Tg):AMPPCP form

Released:
DOI: 10.2210/pdb2c88/pdb
PDB entry 2c88 coloured by chain, front view.
PDB entry 2c88 coloured by chain, side view.
PDB entry 2c88 coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen AM, Sørensen TL, Olesen C, Møller JV, Nissen P
EMBO J 25 2305-14 (2006)
PMID: 16710301

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

4 bound ligands:
Ligand TG1 1 x TG1
Ligand ACP 1 x ACP
Ligand MG 1 x MG
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P41212
Unit cell:
a: 71.529Å b: 71.529Å c: 590.216Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.261 0.261 0.31

Quick links

Citations

19 review citations

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps.
Morth et al. (2011)
18 more

9 mentions without citation

Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen et al. (2006)
8 more