› 2bzx

X-ray diffraction
2.8Å resolution

Atomic model of CrkL-SH3C monomer

Released:
DOI: 10.2210/pdb2bzx/pdb
PDB entry 2bzx coloured by chain, front view.
PDB entry 2bzx coloured by chain, side view.
PDB entry 2bzx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal.
Harkiolaki M, Gilbert RJ, Jones EY, Feller SM
Structure 14 1741-53 (2006)
PMID: 17161365

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155436 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Crk-like protein Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P46109 (Residues: 237-303; Coverage: 22%)
Gene name: CRKL
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P41212
Unit cell:
a: 53.285Å b: 53.285Å c: 51.193Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.317 0.317 0.374
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Regulated unfolding of proteins in signaling.
Mitrea et al. (2013)
7 more

1 mention without citation

Sequence-Based Prediction of Metamorphic Behavior in Proteins.
Chen et al. (2020)