› 2bf1

X-ray diffraction
4Å resolution

Structure of an unliganded and fully-glycosylated SIV gp120 envelope glycoprotein

Released:
DOI: 10.2210/pdb2bf1/pdb
PDB entry 2bf1 coloured by chain, front view.
PDB entry 2bf1 coloured by chain, side view.
PDB entry 2bf1 coloured by chain, top view.
Source organism: Simian immunodeficiency virus
Primary publication:
Structure of an unliganded simian immunodeficiency virus gp120 core.
Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC
Nature 433 834-41 (2005)
PMID: 15729334

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170462 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (8 distinct):
Envelope glycoprotein gp160 Chain: A
Molecule details ›
Chain: A
Length: 316 amino acids
Theoretical weight: 36.83 KDa
Source organism: Simian immunodeficiency virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q07374 (Residues: 64-502; Coverage: 36%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Structure domains: Human immunodeficiency virus 1, Gp160, envelope glycoprotein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, FUC, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P43212
Unit cell:
a: 108.048Å b: 108.048Å c: 117.701Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.385 0.385 0.388
Expression system: Trichoplusia ni

Quick links

Citations

69 review citations

Viral membrane fusion.
Harrison SC. (2008)
68 more

38 mentions without citation

Bioinformatics and molecular modeling in glycobiology.
Frank et al. (2010)
37 more