Function and Biology Details
Reaction catalysed:
H(2) + 5,10-methenyltetrahydromethanopterin = H(+) + 5,10-methylenetetrahydromethanopterin
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- 5,10-methenyltetrahydromethanopterin hydrogenase
- HMD, C-terminal domain superfamily
- 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
- H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase, C-terminal
- NAD(P)-binding domain superfamily
- Methenyltetrahydromethanopterin dehydrogenase, Hmd-type
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
5,10-methenyltetrahydromethanopterin hydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-176577 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5,10-methenyltetrahydromethanopterin hydrogenase
Molecule details ›
Chain: A
Length: 358 amino acids
Theoretical weight: 38.74 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
Sequence domains: H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase
Structure domains:
Length: 358 amino acids
Theoretical weight: 38.74 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
- Canonical:
Q58194 (Residues: 1-358; Coverage: 100%)
Sequence domains: H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X10SA
Spacegroup:
P21212
Expression system: Escherichia coli
