› 2aiv

Solution NMR

Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting domain of NUP116P

Released:
DOI: 10.2210/pdb2aiv/pdb
PDB entry 2aiv coloured by chain, ensemble of 15 models, front view.
PDB entry 2aiv coloured by chain, ensemble of 15 models, side view.
PDB entry 2aiv coloured by chain, ensemble of 15 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM
J Biol Chem 280 35723-32 (2005)
PMID: 16105837

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169733 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP116/NSP116 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.81 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02630 (Residues: 967-1113; Coverage: 13%)
Gene names: NSP116, NUP116, YM9532.12C, YMR047C
Sequence domains: Nucleoporin autopeptidase
Structure domains: Peptidase S59, nucleoporin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

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Citations

3 review citations

The structure of the nuclear pore complex.
Hoelz et al. (2011)
2 more

13 mentions without citation

The yeast nuclear pore complex and transport through it.
Aitchison et al. (2012)
12 more