› 2a6t

X-ray diffraction
2.5Å resolution

Crystal structure of S.pombe mRNA decapping enzyme Dcp2p

Released:
DOI: 10.2210/pdb2a6t/pdb
PDB entry 2a6t coloured by chain, front view.
PDB entry 2a6t coloured by chain, side view.
PDB entry 2a6t coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe.
She M, Decker CJ, Chen N, Tumati S, Parker R, Song H
Nat Struct Mol Biol 13 63-70 (2006)
PMID: 16341225

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126914 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
mRNA decapping complex subunit 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 31.36 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli
UniProt:
  • Canonical: O13828 (Residues: 1-266; Coverage: 36%)
Gene names: SPAC19A8.12, dcp2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P61
Unit cell:
a: 56.481Å b: 56.481Å c: 301.528Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 0.248 0.289
Expression system: Escherichia coli

Quick links

Citations

14 review citations

The control of mRNA decapping and P-body formation.
Franks et al. (2008)
13 more

11 mentions without citation

Length-dependent prediction of protein intrinsic disorder.
Peng et al. (2006)
10 more